Best way to travel between Berlin and Rome

A: Berlin

B: Rome

Travel Modes: Price; Distance; Duration; CO2

bus: $140.0; 1853.35 km; 29h 7mins; 55.6 kgs

flight: $156.0; 1250.52 km; 5h 25mins; 135.06 kgs

drive: $330.0; 1570.4 km; 16h 25mins; 201.01 kgs

train: $412.0; 1891.76 km; 16h 51mins; 100.26 kgs

Tranport	Distance	Time(hrs)	Cost(local)	Cost(usd)
Bus	1853.35 km	29h 7mins	103 EUR	140.0
Flight	1250.52 km	5h 25mins	115 EUR	156.0
Drive	1570.4 km	16h 25mins	243 EUR	330.0
Train	1891.76 km	16h 51mins	303 EUR	412.0

Take Train from Berlin Friedrichstraße to Berlin-Schönefeld Flughafen: Time: 30mins Cost: 11 EUR; $ 13.5 - 16.5 USD CO2 Emission: 1.22 kgs
Take Bus from Berlin Schoenefeld to Praha, ÚAN Florenc: Time: 4h 23mins Cost: 26 EUR; $ 31.5 - 38.5 USD CO2 Emission: 9.83 kgs
Take Bus from Prague - Florenc Station to Rome: Time: 22h 13mins Cost: 66 EUR; $ 81.0 - 99.0 USD CO2 Emission: 45.1 kgs

Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Berlin and Rome is to travel by bus, which will cost about 103 EUR or 126.00 USD.