Best way to travel between Amsterdam, Netherlands and Madrid

A: Amsterdam, Netherlands

B: Madrid

Travel Modes: Price; Distance; Duration; CO2

bus: $126.0; 1902.16 km; 26h 53mins; 57.06 kgs

flight: $182.0; 1597.53 km; 7h 0mins; 172.53 kgs

drive: $380.0; 1836.64 km; 18h 57mins; 235.09 kgs

train: $424.0; 2208.87 km; 14h 16mins; 117.07 kgs

Tranport	Distance	Time(hrs)	Cost(local)	Cost(usd)
Bus	1902.16 km	26h 53mins	93 EUR	126.0
Flight	1597.53 km	7h 0mins	134 EUR	182.0
Drive	1836.64 km	18h 57mins	280 EUR	380.0
Train	2208.87 km	14h 16mins	312 EUR	424.0

Take Bus from Amsterdam Amstel to Paris Gallieni: Time: 7h 48mins Cost: 44 EUR; $ 54.0 - 66.0 USD CO2 Emission: 16.38 kgs
Take Bus from Paris Gallieni to Madrid Sur: Time: 17h 10mins Cost: 48 EUR; $ 58.5 - 71.5 USD CO2 Emission: 39.96 kgs
Take Bus from Mendez Alvaro - Est. Sur de Autobuses to Jacometrezo - Pza. Sto. Domingo: Time: 43mins Cost: 1 EUR; $ 1.8 - 2.2 USD CO2 Emission: 0.73 kgs

Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Amsterdam, Netherlands and Madrid is to travel by bus, which will cost about 93 EUR or 113.40 USD.