Best way to travel between

Frankfurt
Prague
Travel Modes
Price
Distance
Duration
CO2
bus
$30.0
516.11 km
6h 9mins
15.48 kgs
 
train
$100.0
671.65 km
9h 43mins
35.6 kgs
 
drive
$100.0
517.12 km
5h 26mins
66.19 kgs
 
flight
$154.0
444.72 km
4h 7mins
48.03 kgs
 
Tranport Distance Time(hrs) Cost(local) Cost(usd)
Bus 516.11 km 6h 9mins 604 CZK 30.0
Train 671.65 km 9h 43mins 2,014 CZK 100.0
Drive 517.12 km 5h 26mins 2,014 CZK 100.0
Flight 444.72 km 4h 7mins 3,101 CZK 154.0
Take Bus from FrankfurtMain to Prague
Time: 6h 9mins Cost: 604 CZK; $ 27.0 - 33.0 USD CO2 Emission: 15.49 kgs
Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Frankfurt and Prague is to travel by bus, which will cost about 604 CZK or 27.00 USD.