Best way to travel between Guangzhou and Hefei

A: Guangzhou

B: Hefei

Travel Modes: Price; Distance; Duration; CO2

bus: $74.0; 1747.2 km; 19h 34mins; 52.42 kgs

drive: $150.0; 1305.01 km; 13h 14mins; 167.04 kgs

train: $151.0; 1366.8 km; 7h 15mins; 72.44 kgs

flight: $214.0; 1256.64 km; 6h 14mins; 135.72 kgs

Tranport	Distance	Time(hrs)	Cost(local)	Cost(usd)
Bus	1747.2 km	19h 34mins	451 CNY	74.0
Drive	1305.01 km	13h 14mins	915 CNY	150.0
Train	1366.8 km	7h 15mins	921 CNY	151.0
Flight	1256.64 km	6h 14mins	1,305 CNY	214.0

Take Bus from Guangzhou to Nanjing Zhongyangmen: Time: 15h 45mins Cost: 397 CNY; $ 58.5 - 71.5 USD CO2 Emission: 44.56 kgs
Take Bus from Nanjing Zhongyangmen to Wuhu: Time: 1h 3mins Cost: 31 CNY; $ 4.5 - 5.5 USD CO2 Emission: 3.39 kgs
Take Bus from Wuhu to Hefei: Time: 2h 6mins Cost: 37 CNY; $ 5.4 - 6.6 USD CO2 Emission: 4.49 kgs

Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Guangzhou and Hefei is to travel by bus, which will cost about 451 CNY or 66.60 USD.