Best way to travel between Istanbul, Turkey and Berlin

A: Istanbul, Turkey

B: Berlin

Travel Modes: Price; Distance; Duration; CO2

bus: $141.0; 2589.6 km; 45h 4mins; 77.69 kgs

train: $222.0; 2302.8 km; 34h 35mins; 122.05 kgs

flight: $251.0; 1901.55 km; 7h 34mins; 205.37 kgs

drive: $450.0; 2260.96 km; 25h 28mins; 289.4 kgs

Tranport	Distance	Time(hrs)	Cost(local)	Cost(usd)
Bus	2589.6 km	45h 4mins	104 EUR	141.0
Train	2302.8 km	34h 35mins	163 EUR	222.0
Flight	1901.55 km	7h 34mins	185 EUR	251.0
Drive	2260.96 km	25h 28mins	331 EUR	450.0

Take Bus from Istanbul to Burgas: Time: 7h 33mins Cost: 13 EUR; $ 16.2 - 19.8 USD CO2 Emission: 10.48 kgs
Take Bus from Burgas to Berlin ZOB: Time: 36h 5mins Cost: 88 EUR; $ 108.0 - 132.0 USD CO2 Emission: 66.96 kgs
Take Train from Kaiserdamm (U), Berlin to Stadtmitte U2 (U), Berlin: Time: 21mins Cost: 2 EUR; $ 2.7 - 3.3 USD CO2 Emission: 0.47 kgs

Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Istanbul, Turkey and Berlin is to travel by bus, which will cost about 104 EUR or 126.90 USD.