Best way to travel between Istanbul, Turkey and Lisbon

A: Istanbul, Turkey

B: Lisbon

Travel Modes: Price; Distance; Duration; CO2

bus: $192.0; 5329.22 km; 82h 22mins; 159.88 kgs

flight: $265.0; 3413.55 km; 8h 21mins; 368.66 kgs

train: $448.0; 5963.7 km; 62h 4mins; 316.08 kgs

drive: $850.0; 4163.64 km; 43h 57mins; 532.95 kgs

Tranport	Distance	Time(hrs)	Cost(local)	Cost(usd)
Bus	5329.22 km	82h 22mins	141 EUR	192.0
Flight	3413.55 km	8h 21mins	195 EUR	265.0
Train	5963.7 km	62h 4mins	330 EUR	448.0
Drive	4163.64 km	43h 57mins	626 EUR	850.0

Take Bus from Istanbul - Aksaray to Mangalia: Time: 10h 33mins Cost: 17 EUR; $ 20.7 - 25.3 USD CO2 Emission: 17.86 kgs
Take Bus from Mangalia to Cluj: Time: 12h 56mins Cost: 21 EUR; $ 26.1 - 31.9 USD CO2 Emission: 23.56 kgs
Take Bus from Cluj to Lisbona: Time: 56h 49mins Cost: 103 EUR; $ 126.0 - 154.0 USD CO2 Emission: 118.46 kgs

Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Istanbul, Turkey and Lisbon is to travel by bus, which will cost about 141 EUR or 172.80 USD.