Best way to travel between Istanbul, Turkey and Venice

A: Istanbul, Turkey

B: Venice

Travel Modes: Price; Distance; Duration; CO2

bus: $194.0; 1774.69 km; 29h 54mins; 53.24 kgs

flight: $196.0; 1498.65 km; 5h 47mins; 161.85 kgs

train: $211.0; 2344.98 km; 43h 24mins; 124.28 kgs

drive: $370.0; 1778.4 km; 19h 47mins; 227.64 kgs

Tranport	Distance	Time(hrs)	Cost(local)	Cost(usd)
Bus	1774.69 km	29h 54mins	143 EUR	194.0
Flight	1498.65 km	5h 47mins	144 EUR	196.0
Train	2344.98 km	43h 24mins	155 EUR	211.0
Drive	1778.4 km	19h 47mins	272 EUR	370.0

Take Bus from Istanbul to Sofia: Time: 9h 1mins Cost: 33 EUR; $ 40.5 - 49.5 USD CO2 Emission: 17.31 kgs
Take Bus from Sofia to Venezia Mestre Station: Time: 19h 37mins Cost: 103 EUR; $ 126.0 - 154.0 USD CO2 Emission: 35.69 kgs
Take Train from Venezia Mestre to Venezia Santa Lucia: Time: 10mins Cost: 6 EUR; $ 7.2 - 8.8 USD CO2 Emission: 0.46 kgs

Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Istanbul, Turkey and Venice is to travel by bus, which will cost about 143 EUR or 174.60 USD.