Best way to travel between Lisbon and Sao Tome Island

A: Lisbon

B: Sao Tome Island

Travel Modes: Price; Distance; Duration; CO2

bus: $48.0; 364.0 km; 6h 8mins; 10.92 kgs

train: $49.0; 381.1 km; 4h 10mins; 20.2 kgs

drive: $75.0; 352.92 km; 3h 44mins; 45.17 kgs

flight: $104.0; 348.4 km; 4h 27mins; 37.63 kgs

Tranport	Distance	Time(hrs)	Cost(local)	Cost(usd)
Bus	364.0 km	6h 8mins	176 AED	48.0
Train	381.1 km	4h 10mins	180 AED	49.0
Drive	352.92 km	3h 44mins	275 AED	75.0
Flight	348.4 km	4h 27mins	382 AED	104.0

Take Train from Lisboa Santa Apolonia to Lisboa Oriente: Time: 7mins Cost: 37 AED; $ 9.0 - 11.0 USD CO2 Emission: 0.36 kgs
Take Bus from Lisboa to Porto: Time: 4h 26mins Cost: 92 AED; $ 22.5 - 27.5 USD CO2 Emission: 9.58 kgs
Take Train from Porto(Sao Bento) to Vila das Aves-(Negrelos): Time: 50mins Cost: 48 AED; $ 11.7 - 14.3 USD CO2 Emission: 2.06 kgs

Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Lisbon and Sao Tome Island is to travel by bus, which will cost about 176 AED or 43.20 USD.