Best way to travel between Madrid and Frankfurt

A: Madrid

B: Frankfurt

Travel Modes: Price; Distance; Duration; CO2

flight: $85.0; 1510.08 km; 5h 28mins; 163.09 kgs

bus: $166.0; 2072.64 km; 34h 19mins; 62.18 kgs

train: $292.0; 2058.16 km; 17h 19mins; 109.08 kgs

drive: $350.0; 1928.85 km; 19h 49mins; 246.89 kgs

Tranport	Distance	Time(hrs)	Cost(local)	Cost(usd)
Flight	1510.08 km	5h 28mins	63 EUR	85.0
Bus	2072.64 km	34h 19mins	122 EUR	166.0
Train	2058.16 km	17h 19mins	215 EUR	292.0
Drive	1928.85 km	19h 49mins	258 EUR	350.0

Take Train from Recoletos to Aeropuerto T4: Time: 25mins Cost: 2 EUR; $ 2.7 - 3.3 USD CO2 Emission: 0.86 kgs
Take Flight from MAD to FRA: Time: 2h 36mins Cost: 59 EUR; $ 72.0 - 88.0 USD CO2 Emission: 159.88 kgs
Take Train from Frankfurt(M) Flughafen Regionalbf to Frankfurt(M)Hauptwache: Time: 16mins Cost: 1 EUR; $ 1.8 - 2.2 USD CO2 Emission: 0.72 kgs

Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Madrid and Frankfurt is to travel by air, which will cost about 63 EUR or 76.50 USD.