Best way to travel between

Prague
Frankfurt
Travel Modes
Price
Distance
Duration
CO2
bus
$30.0
523.24 km
6h 13mins
15.7 kgs
 
drive
$100.0
519.18 km
5h 25mins
66.46 kgs
 
train
$110.0
698.25 km
9h 59mins
37.01 kgs
 
flight
$167.0
597.92 km
6h 24mins
64.58 kgs
 
Tranport Distance Time(hrs) Cost(local) Cost(usd)
Bus 523.24 km 6h 13mins 22 EUR 30.0
Drive 519.18 km 5h 25mins 74 EUR 100.0
Train 698.25 km 9h 59mins 81 EUR 110.0
Flight 597.92 km 6h 24mins 123 EUR 167.0
Take Bus from Prague to FrankfurtMain
Time: 6h 13mins Cost: 22 EUR; $ 27.0 - 33.0 USD CO2 Emission: 15.72 kgs
Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Prague and Frankfurt is to travel by bus, which will cost about 22 EUR or 27.00 USD.