Best way to travel between Prague and Lyon

A: Prague

B: Lyon

Travel Modes: Price; Distance; Duration; CO2

bus: $80.0; 1317.75 km; 18h 8mins; 39.53 kgs

flight: $173.0; 963.04 km; 7h 23mins; 104.01 kgs

drive: $200.0; 1106.22 km; 11h 20mins; 141.6 kgs

train: $303.0; 1543.28 km; 20h 50mins; 81.79 kgs

Tranport	Distance	Time(hrs)	Cost(local)	Cost(usd)
Bus	1317.75 km	18h 8mins	59 EUR	80.0
Flight	963.04 km	7h 23mins	127 EUR	173.0
Drive	1106.22 km	11h 20mins	147 EUR	200.0
Train	1543.28 km	20h 50mins	223 EUR	303.0

Take Bus from Praha, ÚAN Florenc to Geneva: Time: 13h 39mins Cost: 48 EUR; $ 58.5 - 71.5 USD CO2 Emission: 34.47 kgs
Take Bus from Geneve, Coutance to Geneve,Aeroport(TPG): Time: 18mins Cost: 4 EUR; $ 5.4 - 6.6 USD CO2 Emission: 0.29 kgs
Take Bus from Geneve-Aeroport to Lyon: Time: 3h 4mins Cost: 7 EUR; $ 8.1 - 9.9 USD CO2 Emission: 4.79 kgs

Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Prague and Lyon is to travel by bus, which will cost about 59 EUR or 72.00 USD.