Best way to travel between

Prague
Rome
Travel Modes
Price
Distance
Duration
CO2
flight
$94.0
993.95 km
4h 50mins
107.35 kgs
 
bus
$110.0
1521.84 km
22h 42mins
45.66 kgs
 
train
$140.0
1555.84 km
20h 23mins
82.46 kgs
 
drive
$280.0
1347.24 km
14h 6mins
172.45 kgs
 
Tranport Distance Time(hrs) Cost(local) Cost(usd)
Flight 993.95 km 4h 50mins 69 EUR 94.0
Bus 1521.84 km 22h 42mins 81 EUR 110.0
Train 1555.84 km 20h 23mins 103 EUR 140.0
Drive 1347.24 km 14h 6mins 206 EUR 280.0
Take Bus from Prague Hlavní nádraží Train Station to Prague Ruzyně Airport T1
Time: 34mins Cost: 1 EUR; $ 1.8 - 2.2 USD CO2 Emission: 0.59 kgs
Take Flight from PRG to CIA
Time: 1h 53mins Cost: 66 EUR; $ 81.0 - 99.0 USD CO2 Emission: 103.76 kgs
Take Train from Ciampino to Termini
Time: 15mins Cost: 1 EUR; $ 1.8 - 2.2 USD CO2 Emission: 0.75 kgs
Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Prague and Rome is to travel by air, which will cost about 69 EUR or 84.60 USD.