Best way to travel between

Prague
Vilnius
Travel Modes
Price
Distance
Duration
CO2
bus
$61.13
1449.35 km
26h 50mins
43.48 kgs
 
flight
$132.0
937.38 km
4h 13mins
101.24 kgs
 
drive
$170.0
1103.13 km
15h 9mins
141.2 kgs
 
N/A
 
 
 
 
 
Tranport Distance Time(hrs) Cost(local) Cost(usd)
Bus 1449.35 km 26h 50mins 156 LTL 61.13
Flight 937.38 km 4h 13mins 336 LTL 132.0
Drive 1103.13 km 15h 9mins 432 LTL 170.0
Take Bus from Prague - ÚAN Florenc to Brno
Time: 3h 2mins Cost: 31 LTL; $ 10.8 - 13.2 USD CO2 Emission: 6.28 kgs
Take Bus from Brno to Vilnius
Time: 22h 48mins Cost: 125 LTL; $ 44.2 - 54.0 USD CO2 Emission: 37.22 kgs
Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Prague and Vilnius is to travel by bus, which will cost about 155 LTL or 54.90 USD.