Best way to travel between

Quito
Guayaquil
Travel Modes
Price
Distance
Duration
CO2
bus
$26.0
474.83 km
10h 47mins
14.24 kgs
 
bus
$39.0
563.58 km
8h 24mins
16.91 kgs
 
drive
$68.92
481.95 km
6h 53mins
61.69 kgs
 
flight
$88.0
337.34 km
1h 36mins
36.43 kgs
 
bus
$119.0
487.76 km
6h 41mins
14.63 kgs
 
Tranport Distance Time(hrs) Cost(local) Cost(usd)
Bus 474.83 km 10h 47mins 26 USD 26.0
Bus 563.58 km 8h 24mins 39 USD 39.0
Drive 481.95 km 6h 53mins 69 USD 68.92
Flight 337.34 km 1h 36mins 88 USD 88.0
Bus 487.76 km 6h 41mins 119 USD 119.0
Take Bus from Quito to Ambato
Time: 3h 14mins Cost: 5 USD; $ 4.7 - 5.7 USD CO2 Emission: 4.03 kgs
Take Bus from Ambato to Guayaquil
Time: 6h 26mins Cost: 9 USD; $ 8.1 - 9.9 USD CO2 Emission: 9.93 kgs
Take Car from Guayaquil to Guayaquil
Time: 10mins Cost: 17 USD; $ 15.3 - 18.7 USD CO2 Emission: 1.3 kgs
Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Quito and Guayaquil is to travel by bus, which will cost about 26 USD or 23.40 USD.