Best way to travel between

Rome
Santander
Travel Modes
Price
Distance
Duration
CO2
bus
$163.0
2154.33 km
31h 16mins
64.63 kgs
 
flight
$186.0
1434.79 km
7h 51mins
154.96 kgs
 
train
$189.0
1690.23 km
34h 34mins
89.58 kgs
 
drive
$390.0
1845.76 km
19h 7mins
236.26 kgs
 
Tranport Distance Time(hrs) Cost(local) Cost(usd)
Bus 2154.33 km 31h 16mins 120 EUR 163.0
Flight 1434.79 km 7h 51mins 137 EUR 186.0
Train 1690.23 km 34h 34mins 139 EUR 189.0
Drive 1845.76 km 19h 7mins 287 EUR 390.0
Take Bus from Rome to Barcelona Nord
Time: 19h 57mins Cost: 81 EUR; $ 99.0 - 121.0 USD CO2 Emission: 42.29 kgs
Take Bus from Barcelona to Santander
Time: 10h 18mins Cost: 41 EUR; $ 49.5 - 60.5 USD CO2 Emission: 22.35 kgs
Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Rome and Santander is to travel by bus, which will cost about 120 EUR or 146.70 USD.