Best way to travel between Rome and Vienna

A: Rome

B: Vienna

Travel Modes: Price; Distance; Duration; CO2

bus: $81.0; 1341.3 km; 20h 55mins; 40.24 kgs

flight: $108.0; 898.9 km; 6h 3mins; 97.08 kgs

train: $116.0; 1124.24 km; 14h 30mins; 59.58 kgs

drive: $240.0; 1126.15 km; 11h 46mins; 144.15 kgs

Tranport	Distance	Time(hrs)	Cost(local)	Cost(usd)
Bus	1341.3 km	20h 55mins	60 EUR	81.0
Flight	898.9 km	6h 3mins	80 EUR	108.0
Train	1124.24 km	14h 30mins	85 EUR	116.0
Drive	1126.15 km	11h 46mins	177 EUR	240.0

Take Bus from Rome to Mikulov: Time: 18h 19mins Cost: 55 EUR; $ 67.5 - 82.5 USD CO2 Emission: 37.69 kgs
Take Bus from Mikulov to Vienna - Erdberg: Time: 1h 25mins Cost: 4 EUR; $ 4.5 - 5.5 USD CO2 Emission: 2.44 kgs
Take Train from Erdberg to Stephansplatz: Time: 8mins Cost: 2 EUR; $ 2.7 - 3.3 USD CO2 Emission: 0.2 kgs

Source: Rome2rio

Mode of travel comparision chart

The best and cheapest way to get from Rome and Vienna is to travel by bus, which will cost about 60 EUR or 72.90 USD.